Mouse Monoclonal Antibody to RRM1
货号：
31864
别名：
R1; RR1; RIR1
应用：
WB,IHC,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P23921
规格：
目录价
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Description |
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This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants. |
References |
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| 1.Cancer Biomark. 2018;22(4):657-667. 2.Clin Cancer Res. 2017 Sep 1;23(17):5225-5237. |
Specification |
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|---|---|
| Aliases | R1; RR1; RIR1 |
| Entrez GeneID | 6240 |
| Swissprot | P23921 |
| clone | 2D6D8 |
| WB Predicted band size | 90kDa |
| Host/Isotype | Mouse IgG2a |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human RRM1 (AA: 541-792) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| IHC | 1/200-1/1000 |
| FCM | 1/200-1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)
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Western blot analysis using RRM1 mouse mAb against Hela (1), Jurkat (2), and A431 (3) cell lysate.
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Flow cytometric analysis of Hela cells using RRM1 mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using RRM1 mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using RRM1 mouse mAb with DAB staining.
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