Rabbit Polyclonal Antibody to UBASH3A
货号：
P42623
别名：
Suppressor of T-cell receptor signaling 2; STS-2; Cbl-interacting protein 4; CLIP4; T-cell ubiquitin ligand
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P57075
规格：
目录价
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Description |
|---|
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.Wattenhofer M., Hum. Genet. 108:140-147(2001).Feshchenko E.A., Oncogene 23:4690-4706(2004).Hattori M., Nature 405:311-319(2000). |
Specification |
|
|---|---|
| Aliases | Suppressor of T-cell receptor signaling 2; STS-2; Cbl-interacting protein 4; CLIP4; T-cell ubiquitin ligand |
| Entrez GeneID | 53347; |
| Swissprot | P57075 |
| WB Predicted band size | 74kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from internal of human UBASH3A. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
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