Rabbit Polyclonal Antibody to TCF7L1
货号：
P42640
别名：
Transcription factor 7-like 1; HMG box transcription factor 3; TCF-3; TCF7L1; TCF3
应用：
WB
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q9HCS4
规格：
目录价
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Description |
|---|
Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis By similarity. Down-regulates NQO1, leading to increased mitomycin c resistance.Sagara N., Cancer Res. 60:5959-5962(2000).Hillier L.W., Nature 434:724-731(2005).Castrop J., Nucleic Acids Res. 20:611-611(1992). |
Specification |
|
|---|---|
| Aliases | Transcription factor 7-like 1; HMG box transcription factor 3; TCF-3; TCF7L1; TCF3 |
| Entrez GeneID | 83439; |
| Swissprot | Q9HCS4 |
| WB Predicted band size | 63kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from internal of human TCF7L1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
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