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Rabbit Polyclonal Antibody to ZC3H8
货号: P42671
别名: Zinc finger CCCH domain-containing protein 8; ZC3H8; ZC3HDC8;
应用: WB,IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q8N5P1
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Description

Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene By similarity. Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.Zhuang D.Z., Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.The MGC Project Team, Genome Res. 14:2121-2127(2004).Hwang E.S., Immunology 106:464-469(2002).

Specification

Aliases Zinc finger CCCH domain-containing protein 8; ZC3H8; ZC3HDC8;
Entrez GeneID 84524;
Swissprot Q8N5P1
WB Predicted band size 40kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized peptide derived from internal of human ZC3H8.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
IHC 1/50-1/100
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