Rabbit Polyclonal Antibody to IFIT5
货号：
P42705
别名：
IFIT-5; interferon-induced protein with tetratricopeptide repeats 5; retinoic acid- and interferon-inducible 58 kDa protein; RI58;
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q13325
规格：
目录价
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Description |
|---|
Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs.Rogers J., Nature 429:375-381(2004).Venter J.C., Submitted (SEP-2005).Bennett K.L., Submitted (OCT-2008). |
Specification |
|
|---|---|
| Aliases | IFIT-5; interferon-induced protein with tetratricopeptide repeats 5; retinoic acid- and interferon-inducible 58 kDa protein; RI58; |
| Entrez GeneID | 24138; |
| Swissprot | Q13325 |
| WB Predicted band size | 50kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from internal of human IFIT5. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
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