Rabbit Polyclonal Antibody to GNE
货号:
P42699
别名:
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; UDP-GlcNAc-2-epimerase/ManAc kinase; UDP-N-acetylglucosamine 2-epimerase; UDP-GlcNAc-2-epimerase; Uridine diphosphate-N-acetylglucosamine-2-epimeraseN-acetylmannosamine kinase
应用:
WB,IHC
反应种属:
Human,Mouse
抗体类型:
Primary antibody
Swissprot:
Q9Y223
规格:
目录价
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Description |
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Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Plays an essential role in early development By similarity. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells.Lucka L., FEBS Lett. 454:341-344(1999).Seppala R., Am. J. Hum. Genet. 64:1563-1569(1999).Huizing M., Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases. |
Specification |
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Aliases | Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; UDP-GlcNAc-2-epimerase/ManAc kinase; UDP-N-acetylglucosamine 2-epimerase; UDP-GlcNAc-2-epimerase; Uridine diphosphate-N-acetylglucosamine-2-epimeraseN-acetylmannosamine kinase |
Entrez GeneID | 10020; |
Swissprot | Q9Y223 |
WB Predicted band size | 80kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Synthesized peptide derived from C-terminal of human GNE. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/3000 |
IHC | 1/50-1/100 |