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Rabbit Polyclonal Antibody to GNE
货号: P42699
别名: Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; UDP-GlcNAc-2-epimerase/ManAc kinase; UDP-N-acetylglucosamine 2-epimerase; UDP-GlcNAc-2-epimerase; Uridine diphosphate-N-acetylglucosamine-2-epimeraseN-acetylmannosamine kinase
应用: WB,IHC
反应种属: Human,Mouse
抗体类型: Primary antibody
Swissprot: Q9Y223
规格:
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Description

Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Plays an essential role in early development By similarity. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells.Lucka L., FEBS Lett. 454:341-344(1999).Seppala R., Am. J. Hum. Genet. 64:1563-1569(1999).Huizing M., Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.

Specification

Aliases Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; UDP-GlcNAc-2-epimerase/ManAc kinase; UDP-N-acetylglucosamine 2-epimerase; UDP-GlcNAc-2-epimerase; Uridine diphosphate-N-acetylglucosamine-2-epimeraseN-acetylmannosamine kinase
Entrez GeneID 10020;
Swissprot Q9Y223
WB Predicted band size 80kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Synthesized peptide derived from C-terminal of human GNE.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
IHC 1/50-1/100
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