Rabbit Polyclonal Antibody to TAOK3
货号：
P42695
别名：
Serine/threonine-protein kinase TAO3; Cutaneous T-cell lymphoma-associated antigen HD-CL-09; CTCL-associated antigen HD-CL-09; Dendritic cell-derived protein kinase; JNK/SAPK-inhibitory kinase
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9H2K8
规格：
目录价
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Description |
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Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF).Tassi E., J. Biol. Chem. 274:33287-33295(1999).Zhang W., Biochem. Biophys. Res. Commun. 274:872-879(2000).Yustein J.T., Oncogene 22:6129-6141(2003). |
Specification |
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|---|---|
| Aliases | Serine/threonine-protein kinase TAO3; Cutaneous T-cell lymphoma-associated antigen HD-CL-09; CTCL-associated antigen HD-CL-09; Dendritic cell-derived protein kinase; JNK/SAPK-inhibitory kinase |
| Entrez GeneID | 51347; |
| Swissprot | Q9H2K8 |
| WB Predicted band size | 110kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from internal of human TAOK3. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/500-1/3000 |
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