Rabbit Polyclonal Antibody to ELF4
货号：
P42694
别名：
E74-like factor 4; E74-like factor 4 (ets domain transcription factor); ELFR; ETS-related transcription factor Elf-4; Mef
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q99607
规格：
目录价
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Description |
|---|
Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter By similarity. Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 By similarity. Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway. UniProtKB Q9Z2U4Miyazaki Y., Oncogene 13:1721-1729(1996).Aryee D.N.T., Gene 210:71-78(1998).Ross M.T., Nature 434:325-337(2005). |
Specification |
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|---|---|
| Aliases | E74-like factor 4; E74-like factor 4 (ets domain transcription factor); ELFR; ETS-related transcription factor Elf-4; Mef |
| Entrez GeneID | 2000; |
| Swissprot | Q99607 |
| WB Predicted band size | 70kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from internal of human ELF4. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/500-1/3000 |
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