Rabbit Polyclonal Antibody to FZD1
货号:
P42879
别名:
DKFZp564G072; FLJ95923; Frizzled-1; Fz-1; FZD1; FzE1; hFz1; Wnt receptor
应用:
WB
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q9UP38
规格:
目录价
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Description |
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Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B. |
Specification |
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|---|---|
| Aliases | DKFZp564G072; FLJ95923; Frizzled-1; Fz-1; FZD1; FzE1; hFz1; Wnt receptor |
| Entrez GeneID | 8321; |
| Swissprot | Q9UP38 |
| WB Predicted band size | 71kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide corresponding to residues near the N terminal of human Frizzled family receptor 1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/200-1/1000 |


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