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Rabbit Polyclonal Antibody to AKAP12
货号: P42903
别名: SSeCKS; AKAP250
应用: WB,IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q02952
规格:
目录价
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Description

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Specification

Aliases SSeCKS; AKAP250
Entrez GeneID 9590;
Swissprot Q02952
WB Predicted band size 191kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthetic peptide corresponding to residues near the C terminal of human A kinase (PRKA) anchor protein 12
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/200-1/1000
IHC 1/50-1/200
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