Rabbit Polyclonal Antibody to DUSP2
货号:
P42923
别名:
PAC1; PAC-1
应用:
WB,IHC
反应种属:
Human,Mouse
抗体类型:
Primary antibody
Swissprot:
Q05923
规格:
目录价
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Description |
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The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. |
Specification |
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Aliases | PAC1; PAC-1 |
Entrez GeneID | 1844; |
Swissprot | Q05923 |
WB Predicted band size | 34kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Synthetic peptide corresponding to residues near the C terminal of human dual specificity phosphatase 2 |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/200-1/1000 |
IHC | 1/25-1/100 |