Rabbit Polyclonal Antibody to CERS4
货号：
P42939
别名：
Trh1; LASS4
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9HA82
规格：
目录价
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Description |
|---|
The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis. |
Specification |
|
|---|---|
| Aliases | Trh1; LASS4 |
| Entrez GeneID | 79603; |
| Swissprot | Q9HA82 |
| WB Predicted band size | 46kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human ceramide synthase 4 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/2000 |
| IHC | 1/50-1/200 |
Product Image
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Gel: 8%SDS-PAGE Lysates (from left to right): Human fetal liver tissue, HT-29 and HUVEC cell, MCF-7 cell and human hepatocellular carcinoma tissue Amount of lysate: 40ug per lane Primary antibody: 1/300 dilution Secondary antibody dilution: 1/8000 Exposure time: 10 seconds
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Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using P42939 at dilution 1/35.
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