Mouse Monoclonal Antibody to CD137
货号：
31912
别名：
TNFRSF9; ILA; 4-1BB; CDw137
应用：
WB,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q07011
规格：
目录价
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Description |
|---|
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. |
References |
|---|
| 1.Blood. 2019 Oct 31;134(18):1510-1516. 2.Cancer Commun (Lond). 2019 Jul 9;39(1):41. |
Specification |
|
|---|---|
| Aliases | TNFRSF9; ILA; 4-1BB; CDw137 |
| Entrez GeneID | 3604 |
| Swissprot | Q07011 |
| clone | 2C6B4 |
| WB Predicted band size | 27.9kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD137 (AA: 214-255) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| FCM | 1/200-1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)
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Western blot analysis using CD137 mouse mAb against HepG2 (1), Jurkat (2), MOLT4 (3), HL-60 (4), THP-1 (5), Ramos (6), K562 (7), and Raji (8) cell lysate.
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Flow cytometric analysis of HL-60 cells using CD137 mouse mAb (green) and negative control (red).
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Flow cytometric analysis of THP-1 cells using CD137 mouse mAb (green) and negative control (red).
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