Mouse Monoclonal Antibody to CHGA
货号:
31948
别名:
CGA
应用:
WB,IHC,FCM
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P10645
规格:
目录价
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Description |
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The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene. |
References |
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1,Mol Omics. 2019 Feb 11;15(1):67-76; 2,Int J Mol Sci. 2019 Jun 14;20(12):2919;3,Pancreas. May/Jun 2019;48(5):662-669. |
Specification |
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Aliases | CGA |
Entrez GeneID | 1113 |
Swissprot | P10645 |
clone | 5H10B12 |
WB Predicted band size | 50kDa |
Host/Isotype | Mouse IgG2b |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CHGA (AA: 278-457) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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WB | 1/500 - 1/2000 |
IHC | 1/200-1/1000 |
FCM | 1/200-1/400 |
ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)
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Western blot analysis using CHGA mouse mAb against SH-SY5Y (1) cell lysate.
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Flow cytometric analysis of C6 cells using CHGA mouse mAb (green) and negative control (red).
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Flow cytometric analysis of Hela cells using CHGA mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human pancreatic tissues using CHGA mouse mAb with DAB staining.