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Mouse Monoclonal Antibody to CHGA
货号: 31948
别名: CGA
应用: WB,IHC,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P10645
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Description

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene.

References

1,Mol Omics. 2019 Feb 11;15(1):67-76;
2,Int J Mol Sci. 2019 Jun 14;20(12):2919;3,Pancreas. May/Jun 2019;48(5):662-669.

Specification

Aliases CGA
Entrez GeneID 1113
Swissprot P10645
clone 5H10B12
WB Predicted band size 50kDa
Host/Isotype Mouse IgG2b
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CHGA (AA: 278-457) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
IHC 1/200-1/1000
FCM 1/200-1/400
ELISA 1/10000
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