Rabbit Polyclonal Antibody to FZR1
货号：
P43418
别名：
FZR; CDH1; FZR2; HCDH; HCDH1; CDC20C
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9UM11
规格：
目录价
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Description |
|---|
Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. |
Specification |
|
|---|---|
| Aliases | FZR; CDH1; FZR2; HCDH; HCDH1; CDC20C |
| Entrez GeneID | 51343; |
| Swissprot | Q9UM11 |
| WB Predicted band size | 55kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein of human FZR1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/2000 |
| IHC | 1/25-1/100 |
Product Image
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Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Human placenta tissue Primary antibody: 1/400 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 3 minutes
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Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using P43418 at dilution 1/20.
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Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using P43418 at dilution 1/20.
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