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Rabbit Polyclonal Antibody to SSRP1
货号: P43428
别名: FACT; T160; FACT80
应用: WB,IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q08945
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Description

The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA.

Specification

Aliases FACT; T160; FACT80
Entrez GeneID 6749;
Swissprot Q08945
WB Predicted band size 81kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Fusion protein of human SSRP1
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/2000
IHC 1/25-1/100
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