Rabbit Polyclonal Antibody to Rb (phospho Ser249)
货号：
P44123
别名：
RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110
应用：
IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P06400
规格：
目录价
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Description |
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RB transcriptional corepressor 1(RB1) Homo sapiens The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008], |
Specification |
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|---|---|
| Aliases | RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110 |
| Entrez GeneID | 5925 |
| Swissprot | P06400 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Retinoblastoma around the phosphorylation site of Ser249. AA range:221-270 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
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|---|---|
| IF | 1/200 - 1/1000 |
| ELISA | 1/5000 |
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