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Rabbit Polyclonal Antibody to PKR (phospho Thr258)
货号: P44157
别名: EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k
应用: WB,IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: P19525
规格:
目录价
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Description

eukaryotic translation initiation factor 2 alpha kinase 2(EIF2AK2) Homo sapiens The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],

Specification

Aliases EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k
Entrez GeneID 5610
Swissprot P19525
WB Predicted band size 62kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen The antiserum was produced against synthesized peptide derived from human PKR around the phosphorylation site of Thr258. AA range:226-275
Formulation Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

Application

WB 1/500 - 1/2000
IHC 1/100 - 1/300
ELISA 1/20000

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