Rabbit Polyclonal Antibody to Catenin-β (phospho Ser37)
货号：
P44550
别名：
CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P35222
规格：
目录价
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Description |
|---|
catenin beta 1(CTNNB1) Homo sapiens The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016], |
Specification |
|
|---|---|
| Aliases | CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin |
| Entrez GeneID | 1499 |
| Swissprot | P35222 |
| WB Predicted band size | 85kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Catenin-beta around the phosphorylation site of Ser37. AA range:3-52 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| IHC | 1/100 - 1/300 |
| IF | 1/200 - 1/1000 |
| ELISA | 1/40000 |
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