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Rabbit Polyclonal Antibody to Artemis (phospho Ser516)
货号: P44622
别名: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C; Protein artemis; DNA cross-link repair 1C protein; Protein A-SCID; SNM1 homolog C; hSNM1C; SNM1-like protein
应用: WB,IHC
反应种属: Human,Mouse
抗体类型: Primary antibody
Swissprot: Q96SD1
规格:
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Description

DNA cross-link repair 1C(DCLRE1C) Homo sapiens This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5‘-3‘ exonuclease activity; it also exhibits endonuclease activity on 5‘ and 3‘ overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],

Specification

Aliases DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C; Protein artemis; DNA cross-link repair 1C protein; Protein A-SCID; SNM1 homolog C; hSNM1C; SNM1-like protein
Entrez GeneID 64421
Swissprot Q96SD1
WB Predicted band size 78kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen The antiserum was produced against synthesized peptide derived from human Artemis around the phosphorylation site of Ser516. AA range:482-531
Formulation Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

Application

WB 1/500 - 1/2000
IHC 1/100 - 1/300
ELISA 1/5000

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