Mouse Monoclonal Antibody to MERTK
货号：
32084
别名：
MER; RP38; c-Eyk; c-mer; Tyro12
应用：
WB,IF,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q12866
规格：
目录价
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Description |
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This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). |
References |
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| 1,PLoS One. 2019 Dec 5;14(12):e0225051. 2,Can J Ophthalmol. 2019 Feb;54(1):40-50. |
Specification |
|
|---|---|
| Aliases | MER; RP38; c-Eyk; c-mer; Tyro12 |
| Entrez GeneID | 10461 |
| Swissprot | Q12866 |
| clone | 3D11G8 |
| WB Predicted band size | 140-180 kDa |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human MERTK (AA:extra(21-220)) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| IF | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Western blot analysis using MERTK mouse mAb against HepG2 (1), and PANC-1 (2) cell lysate.
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Immunofluorescence analysis of Hela cells using MERTK mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
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Flow cytometric analysis of bel-7402 cells using MERTK mouse mAb (green) and negative control (red).
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Flow cytometric analysis of HepG2 cells using MERTK mouse mAb (green) and negative control (red).
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Flow cytometric analysis of U937 cells using MERTK mouse mAb (green) and negative control (red).
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