Mouse Monoclonal Antibody to C5AR2
货号:
32083
别名:
C5L2; GPF77; GPR77
应用:
WB,IHC,FCM
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q9P296
规格:
目录价
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Description |
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This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. |
References |
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1,Oncotarget. 2017 Jan 31;8(5):8590-8596. 2,J Dent Res. 2017 Jan;96(1):92-99. |
Specification |
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Aliases | C5L2; GPF77; GPR77 |
Entrez GeneID | 27202 |
Swissprot | Q9P296 |
clone | 6D4A4 |
WB Predicted band size | 36kDa |
Host/Isotype | Mouse IgG2b |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human C5AR2 (AA: extra mix) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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WB | 1/500 - 1/2000 |
IHC | 1/200 - 1/1000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Western blot analysis using C5AR2 mouse mAb against K562 (1),THP-1 (2), and MOLT4 (3) cell lysate.
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Flow cytometric analysis of MOLT4 cells using C5AR2 mouse mAb (green) and negative control (red).
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Flow cytometric analysis of HL-60 cells using C5AR2 mouse mAb (green) and negative control (red).
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Flow cytometric analysis of RAW264.7 cells using C5AR2 mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human liver cancer tissues using C5AR2 mouse mAb with DAB staining.