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Mouse Monoclonal Antibody to C5AR2
货号: 32083
别名: C5L2; GPF77; GPR77
应用: WB,IHC,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q9P296
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Description

This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants.

References

1,Oncotarget. 2017 Jan 31;8(5):8590-8596.
2,J Dent Res. 2017 Jan;96(1):92-99.

Specification

Aliases C5L2; GPF77; GPR77
Entrez GeneID 27202
Swissprot Q9P296
clone 6D4A4
WB Predicted band size 36kDa
Host/Isotype Mouse IgG2b
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human C5AR2 (AA: extra mix) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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