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Mouse Monoclonal Antibody to CD151
货号: 32094
别名: GP27; MER2; RAPH; SFA1; PETA-3; TSPAN24
应用: IHC,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P48509 
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Description

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.

References

1.J Cell Sci. 2019 Oct 10;132(19):jcs235366.
2.Cell Mol Life Sci. 2019 Apr;76(8):1595-1604.

Specification

Aliases GP27; MER2; RAPH; SFA1; PETA-3; TSPAN24
Entrez GeneID 977
Swissprot P48509 
clone 2B1F2
WB Predicted band size 28.3kDa
Host/Isotype Mouse IgG2a
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CD151 (AA: extra 113-221) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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