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Mouse Monoclonal Antibody to MR1
货号: 32124
别名: HLALS
应用: IHC,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q95460
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Description

MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.

References

1,Sci Rep. 2020 Sep 22;10(1):15429.
2,Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):24974-24985.

Specification

Aliases HLALS
Entrez GeneID 3140
Swissprot Q95460
clone 6A5B2
WB Predicted band size 39.4kda
Host/Isotype Mouse IgG2a
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human MR1 (AA: extra(23-302)) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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