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Mouse Monoclonal Antibody to GZMK
货号: 32129
别名: TRYP2
应用: IHC,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P49863
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Description

This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008]

References

1,Brain. 2019 Nov 1;142(11):3411-3427.
2,J Invest Dermatol. 2019 Apr;139(4):930-939.

Specification

Aliases TRYP2
Entrez GeneID 3003
Swissprot P49863
clone 2F9C12
WB Predicted band size 29kda
Host/Isotype Mouse IgG2b
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human GZMK (AA: 27-264) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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