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Mouse Monoclonal Antibody to PDLIM7
货号: 32137
别名: LMP1; LMP3
应用: IHC,IF,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q9NR12
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Description

The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.

References

1.Med Sci Monit. 2018 Oct 25;24:7603-7613.
2.Oncol Rep. 2015 May;33(5):2253-60.

Specification

Aliases LMP1; LMP3
Entrez GeneID 9260
Swissprot Q9NR12
clone 3B3B3
WB Predicted band size 49.8kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human PDLIM7 (AA: 86-280) expressed in HEK293-6e cells supernatant.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IHC 1/200 - 1/1000
IF 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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