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Mouse Monoclonal Antibody to CD1D
货号: 32162
别名: R3; CD1A; R3G1
应用: FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P15813 
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Description

This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene.

References

1.Cancer Med. 2019 Nov;8(16):7065-7073.
2.Brain Pathol2020 Jan;30(1):26-35.

Specification

Aliases R3; CD1A; R3G1
Entrez GeneID 912
Swissprot P15813 
clone 3A6G3
WB Predicted band size 37.7kDa
Host/Isotype Mouse IgG2b
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CD1D (AA: extra 20-301) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

FCM 1/200 - 1/400
ELISA 1/10000
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