Mouse Monoclonal Antibody to PTGS2
货号：
32175
别名：
COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS
应用：
IF,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P35354
规格：
目录价
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Description |
|---|
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. |
References |
|---|
| 1,PLoS One. 2020 Sep 30;15(9):e0239856. 2,Acta Gastroenterol Belg. Apr-Jun 2020;83(2):249-254. |
Specification |
|
|---|---|
| Aliases | COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS |
| Entrez GeneID | 5743 |
| Swissprot | P35354 |
| clone | 4C1H7 |
| WB Predicted band size | 69kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human PTGS2 (AA: 18-207) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| IF | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Immunofluorescence analysis of Hela cells using PTGS2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
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Flow cytometric analysis of Hela cells using PTGS2 mouse mAb (green) and negative control (red).
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Flow cytometric analysis of HepG2 cells using PTGS2 mouse mAb (green) and negative control (red).
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Flow cytometric analysis of HT-29 cells using PTGS2 mouse mAb (green) and negative control (red).
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