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Mouse Monoclonal Antibody to TNFRSF10A
货号: 32172
别名: DR4; APO2; CD261; TRAILR1; TRAILR-1
应用: FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: O00220
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Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.

References

1.Int J Cancer. 2018 Jul 15;143(2):289-297.
2.BMC Cancer. 2018 Jul 31;18(1):777.

Specification

Aliases DR4; APO2; CD261; TRAILR1; TRAILR-1
Entrez GeneID 8797
Swissprot O00220
clone 4A4A9
WB Predicted band size 50kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human TNFRSF10A (AA: extra 24-239) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

FCM 1/200 - 1/400
ELISA 1/10000
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