Mouse Monoclonal Antibody to M6PR
货号:
32211
别名:
SMPR; MPR46; CD-MPR; MPR 46; MPR-46; CD-M6PR
应用:
WB,IHC,FCM
反应种属:
Human, Mouse
抗体类型:
Primary antibody
Swissprot:
P20645
规格:
目录价
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Description |
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This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. |
References |
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1.Cell Mol Immunol. 2018 Nov;15(11):986-988. 2.Biochemistry. 2010 Jan 12;49(1):236-46. |
Specification |
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Aliases | SMPR; MPR46; CD-MPR; MPR 46; MPR-46; CD-M6PR |
Entrez GeneID | 4074 |
Swissprot | P20645 |
clone | 1B11C1 |
WB Predicted band size | 30.9kDa |
Host/Isotype | Mouse IgG2b |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Purified recombinant fragment of human M6PR (AA: 124-277) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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WB | 1/500 - 1/2000 |
IHC | 1/200 - 1/1000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Western blot analysis using M6PR mouse mAb against mouse brain (1) and HepG2 (2) cell lysate.
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Flow cytometric analysis of THP-1 cells using M6PR mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissues using M6PR mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human brain tissues using M6PR mouse mAb with DAB staining.