Mouse Monoclonal Antibody to XRCC1
货号：
32226
别名：
RCC; SCAR26
应用：
WB,IHC,FCM
反应种属：
Human, Monkey
抗体类型：
Primary antibody
Swissprot：
P18887
规格：
目录价
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Description |
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The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |
References |
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| 1,Zhonghua Yi Xue Za Zhi. 2021 Mar 23;101(11):759-765. 2,Meta-Analysis Biomed Res Int. 2020 Oct 22;2020:3520764. |
Specification |
|
|---|---|
| Aliases | RCC; SCAR26 |
| Entrez GeneID | 7515 |
| Swissprot | P18887 |
| clone | 7B4C12 |
| WB Predicted band size | 69.5kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Monkey |
| Immunogen | Purified recombinant fragment of human XRCC1 (AA:1-150) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| IHC | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Western blot analysis using XRCC1 mouse mAb against Hela (1), Jurkat (2),k562 (3),SK-OV-3 (4), and COS-7 (5) cell lysate.
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Flow cytometric analysis of Jurkat cells using XRCC1 mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human bladder Cancer tissues using Jurkat mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissues using Jurkat mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human rectal cancer tissues using Jurkat mouse mAb with DAB staining.
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