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Mouse Monoclonal Antibody to ALDH1L1
货号: 32286
别名: FDH; FTHFD; 10-fTHF; 10-FTHFDH
应用: WB,IHC,FCM
反应种属: Human, Mouse, Rat
抗体类型: Primary antibody
Swissprot: O75891
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Description

The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants.

References

1.Chem Biol Interact. 2017 Oct 1;276:23-30.
2.Oncotarget. 2016 Aug 2;7(31):49397-49410.

Specification

Aliases FDH; FTHFD; 10-fTHF; 10-FTHFDH
Entrez GeneID 10840
Swissprot O75891
clone 1B5E1
WB Predicted band size 98.8kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Purified recombinant fragment of human ALDH1L1 (AA: 10-222) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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