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Mouse Monoclonal Antibody to CCNB3
货号: 32310
别名: CYCB3
应用: FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q8WWL7
规格:
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Description

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as positive regulators of cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle. Different cyclins exhibit distinct expression and degradation patterns, which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chicken and drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and may be required for proper spindle reorganization and restoration of the interphase nucleus. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

References

1.Pediatr Blood Cancer. 2020 Apr;67(4):e28151.
2.Am J Surg Pathol. 2017 Dec;41(12):1713-1721.

Specification

Aliases CYCB3
Entrez GeneID 85417
Swissprot Q8WWL7
clone 4B4D8
WB Predicted band size 158kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CCNB3 (AA: 142-363) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

FCM 1/200 - 1/400
ELISA 1/10000
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