Mouse Monoclonal Antibody to CCNB3
货号:
32310
别名:
CYCB3
应用:
FCM
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q8WWL7
规格:
目录价
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Description |
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The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as positive regulators of cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle. Different cyclins exhibit distinct expression and degradation patterns, which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chicken and drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and may be required for proper spindle reorganization and restoration of the interphase nucleus. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
References |
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1.Pediatr Blood Cancer. 2020 Apr;67(4):e28151. 2.Am J Surg Pathol. 2017 Dec;41(12):1713-1721. |
Specification |
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Aliases | CYCB3 |
Entrez GeneID | 85417 |
Swissprot | Q8WWL7 |
clone | 4B4D8 |
WB Predicted band size | 158kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CCNB3 (AA: 142-363) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Flow cytometric analysis of Hela cells using CCNB3 mouse mAb (green) and negative control (red).
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Flow cytometric analysis of Jurkat cells using CCNB3 mouse mAb (green) and negative control (red).