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Mouse Monoclonal Antibody to TNNT2
货号: 32323
别名: CMH2; RCM3; TnTC; cTnT; CMD1D; CMPD2; LVNC6
应用: WB,IHC,FCM
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: P45379
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Description

The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

References

1.Oncol Rep. 2020 Aug;44(2):628-636.
2.J Am Heart Assoc. 2020 Apr 21;9(8):e015316.

Specification

Aliases CMH2; RCM3; TnTC; cTnT; CMD1D; CMPD2; LVNC6
Entrez GeneID 7139
Swissprot P45379
clone 4A6E5
WB Predicted band size 35.9kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Purified recombinant fragment of human TNNT2 (AA: full 1-295) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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