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Mouse Monoclonal Antibody to IFNAR1
货号: 32364
别名: AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC
应用: WB,IHC,FCM
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: P17181
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Description

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor.

References

1.J Clin Invest. 2021 Jan 4;131(1):e139980.
2.Front Immunol. 2021 Mar 5;12:628364.

Specification

Aliases AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC
Entrez GeneID 3454
Swissprot P17181
clone 2A5B12
WB Predicted band size 63.5kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Purified recombinant fragment of human IFNAR1 (AA: 28-156) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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