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Mouse Monoclonal Antibody to PARK7
货号: 32363
别名: DJ1; DJ-1; GATD2; HEL-S-67p
应用: WB,IHC,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q99497
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Description

The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.

References

1.Biochemistry (Mosc). 2021 Jun;86(6):627-640.
2.Sci Rep. 2021 Jul 16;11(1):14582.

Specification

Aliases DJ1; DJ-1; GATD2; HEL-S-67p
Entrez GeneID 11315
Swissprot Q99497
clone 2B1D7
WB Predicted band size 19.8kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human PARK7 (AA: 1-189) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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