Mouse Monoclonal Antibody to SH2B2
货号：
32372
别名：
APS
应用：
IHC,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
O14492
规格：
目录价
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Description |
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The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. |
References |
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| 1.Cancer Epidemiol Biomarkers Prev. 2002 Jul;11(7):664-9. 2.J Biol Chem. 2005 May 13;280(19):18943-9. |
Specification |
|
|---|---|
| Aliases | APS |
| Entrez GeneID | 10603 |
| Swissprot | O14492 |
| clone | 5E11G7 |
| WB Predicted band size | 67.7kDa |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human SH2B2 (AA: 497-676) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| IHC | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Flow cytometric analysis of HEK293 cells using SH2B2 mouse mAb (green) and negative control (red).
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Flow cytometric analysis of HepG2 cells using SH2B2 mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using SH2B2 mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human colon cancer tissues using SH2B2 mouse mAb with DAB staining.
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