Mouse Monoclonal Antibody to MSH6
货号：
20192
别名：
GTBP; HSAP; HNPCC5
应用：
FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P52701
规格：
目录价
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Description |
|---|
Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair. |
References |
|---|
| 1. Oncology (Williston Park). 2005 Apr;19(4):455-63. 2. Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):558-63. |
Specification |
|
|---|---|
| Aliases | GTBP; HSAP; HNPCC5 |
| Entrez GeneID | 2956 |
| Swissprot | P52701 |
| clone | 3A10H7 |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of MSH6 expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application |
|
|---|---|
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
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