Mouse Monoclonal Antibody to IGFBP2
货号：
20204
别名：
IBP2; IGF-BP53
应用：
IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P18065
规格：
目录价
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Description |
|---|
IGFBP2: insulin-like growth factor binding protein 2. IGFBP2 is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of other cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness. |
References |
|---|
| 1. Oncol Rep. 2005 Feb;13(2):341-5. 2. Prostate. 2005 Jun 15;64(1):9-19. 3. Bone. 2005 Dec;37(6):741-50. |
Specification |
|
|---|---|
| Aliases | IBP2; IGF-BP53 |
| Entrez GeneID | 3485 |
| Swissprot | P18065 |
| clone | 1F6F6 |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of protein IGFBP2 (aa180-328) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| IHC | 1/200 - 1/1000 |
| ELISA | 1/10000 |
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