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Rabbit Polyclonal Antibody to IL1R2
货号: P00126
别名: IL1RB, CD121b, CDw121b, IL-1R-2, IL-1RT2, IL-1RT-2
应用: IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: P27930
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Description

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.

Specification

Aliases IL1RB, CD121b, CDw121b, IL-1R-2, IL-1RT2, IL-1RT-2
Swissprot P27930
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Fusion protein of human IL1R2
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

IHC 1/25-1/200
ELISA 1/1000-1/5000
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