Rabbit Polyclonal Antibody to IL1R2
货号:
P00126
别名:
IL1RB, CD121b, CDw121b, IL-1R-2, IL-1RT2, IL-1RT-2
应用:
IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P27930
规格:
目录价
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Description |
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The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. |
Specification |
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Aliases | IL1RB, CD121b, CDw121b, IL-1R-2, IL-1RT2, IL-1RT-2 |
Swissprot | P27930 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Fusion protein of human IL1R2 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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IHC | 1/25-1/200 |
ELISA | 1/1000-1/5000 |