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Rabbit Polyclonal Antibody to CTNNAL1
货号: P00231
别名: ACRP; CLLP; alpha-CATU
应用: IHC
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: Q9UBT7
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Description

CTNNAL1 (catenin (cadherin-associated protein), alpha-like 1), also known as CLLP or alpha-CATU, is a 734 amino acid cytoplasmic peripheral membrane protein belonging to the vinculin/alpha-catenin family. Expressed at high levels in adrenal gland and present at lower levels in neural tissues, CTNNAL1 may be involved in the regulation of Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor 1 (RhoGEF p115). It is suggested that CTNNAL1 is down-regulated in pancreatic carcinoma undergoing differentiation and apoptosis. Existing as three isforms produced by alternative splicing events, CTNNAL1 may contribute to the wound repair and proliferation of human bronchial epithelial cells (HBEC).

Specification

Aliases ACRP; CLLP; alpha-CATU
Swissprot Q9UBT7
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Fusion protein of human CTNNAL1
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

IHC 1/30-1/150
ELISA 1/5000-1/10000
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