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Rabbit Polyclonal Antibody to BIRC7
货号: P00501
别名: KIAP; LIVIN; MLIAP; RNF50; ML-IAP
应用: WB,IHC
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: Q96CA5
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Description

This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants.

Specification

Aliases KIAP; LIVIN; MLIAP; RNF50; ML-IAP
Swissprot Q96CA5
WB Predicted band size 33 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Fusion protein of human BIRC7
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/500-1/2000
IHC 1/50-1/200
ELISA 1/5000-1/10000
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