Rabbit Polyclonal Antibody to COPS5
货号：
P00484
别名：
CSN5, JAB1, SGN5, MOV-34
应用：
WB,IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q92905
规格：
目录价
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Description |
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The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors |
Specification |
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|---|---|
| Aliases | CSN5, JAB1, SGN5, MOV-34 |
| Swissprot | Q92905 |
| WB Predicted band size | 38 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human COPS5 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/5000 |
| IHC | 1/150-1/500 |
| ELISA | 1/2000-1/10000 |
Product Image
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Gel: 12%SDS-PAGE, Lysate: 30 μg, Lane: Mouse liver tissue, Primary antibody: P00484(COPS5 Antibody) at dilution 1/1550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
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The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P00484(COPS5 Antibody) at dilution 1/120. (Original magnification: ×200)
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