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Rabbit Polyclonal Antibody to MAP2K5
货号: P00591
别名: MEK5, MAPKK5, PRKMK5, HsT17454
应用: IHC
反应种属: Human, Mouse, Rat
抗体类型: Primary antibody
Swissprot: Q13163
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Description

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.

Specification

Aliases MEK5, MAPKK5, PRKMK5, HsT17454
Swissprot Q13163
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Fusion protein of human MAP2K5
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

IHC 1/50-1/200
ELISA 1/2000-1/5000
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