Rabbit Polyclonal Antibody to TNFRSF11B
货号:
P00586
别名:
OPG, TR1, OCIF
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
O00300
规格:
目录价
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Description |
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. |
Specification |
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Aliases | OPG, TR1, OCIF |
Swissprot | O00300 |
WB Predicted band size | 46 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Fusion protein of human TNFRSF11B |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/500-1/2000 |
IHC | 1/25-1/100 |
ELISA | 1/2000-1/5000 |
Product Image
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Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse kidney tissue, Primary antibody: P00586(TNFRSF11B Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P00586(TNFRSF11B Antibody) at dilution 1/30. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P00586(TNFRSF11B Antibody) at dilution 1/30. (Original magnification: ×200)