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Rabbit Polyclonal Antibody to TNFRSF11B
货号: P00586
别名: OPG, TR1, OCIF
应用: WB,IHC
反应种属: Human, Mouse, Rat
抗体类型: Primary antibody
Swissprot: O00300
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Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Specification

Aliases OPG, TR1, OCIF
Swissprot O00300
WB Predicted band size 46 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Fusion protein of human TNFRSF11B
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/500-1/2000
IHC 1/25-1/100
ELISA 1/2000-1/5000
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