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Mouse Monoclonal Antibody to SND1/P100
货号: 20229
别名: p100; TDRD11; TudorSN
应用: WB
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q7KZF4
规格:
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Description

SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, it functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activatior of EBNA-2. It also interacts with EAV, NSP1,GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.

References

1. J Gen Virol. 2003 Sep;84(Pt 9):2317-22.
2. Biochim Biophys Acta. 2005 Jan 11;1681(2-3):126-33.

Specification

Aliases p100; TDRD11; TudorSN
Entrez GeneID 27044
Swissprot Q7KZF4
clone 2D7
WB Predicted band size 102kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of SND1 (aa361-485) expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

WB 1/500 - 1/2000
ELISA 1/10000
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