Rabbit Polyclonal Antibody to EPS15L1
货号:
P01002
别名:
EPS15R
应用:
WB,IHC
反应种属:
Human, Mouse
抗体类型:
Primary antibody
Swissprot:
Q9UBC2
规格:
目录价
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Description |
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Epidermal growth factor receptor substrate 15-like 1 is a protein that in humans is encoded by the EPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2. |
Specification |
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Aliases | EPS15R |
Swissprot | Q9UBC2 |
WB Predicted band size | 94 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Fusion protein of human EPS15L1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/500-1/2000 |
IHC | 1/25-1/100 |
ELISA | 1/2000-1/5000 |
Product Image
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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Hela cells, PC3 cells, 231 cells, 293T cells, Primary antibody: P01002(EPS15L1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P01002(EPS15L1 Antibody) at dilution 1/30. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P01002(EPS15L1 Antibody) at dilution 1/30. (Original magnification: ×200)