Rabbit Polyclonal Antibody to LIMS1
货号:
P01516
别名:
PINCH; PINCH1; PINCH-1
应用:
WB,IHC
反应种属:
Human, Mouse
抗体类型:
Primary antibody
Swissprot:
P48059
规格:
目录价
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Description |
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The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. |
Specification |
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Aliases | PINCH; PINCH1; PINCH-1 |
Swissprot | P48059 |
WB Predicted band size | 37 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Fusion protein of human LIMS1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/500-1/2000 |
IHC | 1/50-1/200 |
ELISA | 1/2000-1/5000 |
Product Image
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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human kidney tissue, mouse lung tissue, Primary antibody: P01516(LIMS1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
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The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P01516(LIMS1 Antibody) at dilution 1/40. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P01516(LIMS1 Antibody) at dilution 1/40. (Original magnification: ×200)