Rabbit Polyclonal Antibody to MRE11
货号:
P01553
别名:
ATLD; HNGS1; MRE11A; MRE11B
应用:
WB,IHC
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
P49959
规格:
目录价
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Description |
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This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
Specification |
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Aliases | ATLD; HNGS1; MRE11A; MRE11B |
Swissprot | P49959 |
WB Predicted band size | 81 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Fusion protein of human MRE11 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/500-1/2000 |
IHC | 1/100-1/300 |
ELISA | 1/2000-1/5000 |
Product Image
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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Raji cells, K562 cells, Primary antibody: P01553(MRE11 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
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The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P01553(MRE11 Antibody) at dilution 1/60. (Original magnification: ×200)
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The image is immunohistochemistry of paraffin-embedded Human brain tissue using P01553(MRE11 Antibody) at dilution 1/60. (Original magnification: ×200)