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Rabbit Polyclonal Antibody to RAE1
货号: P01698
别名: Gle2; MIG14; MRNP41; Mnrp41; dJ481F12.3; dJ800J21.1
应用: WB,IHC
反应种属: Human, Mouse, Rat
抗体类型: Primary antibody
Swissprot: P78406
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Description

Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Specification

Aliases Gle2; MIG14; MRNP41; Mnrp41; dJ481F12.3; dJ800J21.1
Swissprot P78406
WB Predicted band size 41 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Fusion protein of human RAE1
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/1000-1/5000
IHC 1/150-1/300
ELISA 1/5000-1/10000
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